Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 5/20 | 0.47 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942097 | 1.00 | CAPN1 (0.53) | CAPN1AKR1C3CTSLCTSBGGPS1 | |
| SCHEMBL6944325 | 0.87 | AKR1C3 (0.48) | CAPN1AKR1C3GGPS1CA2PLG | |
| SCHEMBL6942392 | 0.87 | AKR1C3 (0.48) | CAPN1AKR1C3GGPS1CA2PLG | |
| SCHEMBL7322714 | 0.85 | AKR1C3 (0.51) | AKR1C3GGPS1PLGMEN1KMT2A | |
| SCHEMBL7325437 | 0.84 | CAPN1 (0.52) | CAPN1AKR1C3CTSLCTSBGGPS1 | |
| SCHEMBL7692550 | 0.84 | AKR1C3 (0.51) | AKR1C3GGPS1CA2MEN1KMT2A | |
| SCHEMBL6939223 | 0.84 | CAPN1 (0.52) | CAPN1AKR1C3CTSLCTSBGGPS1 | |
| SCHEMBL7694179 | 0.84 | AKR1C3 (0.48) | AKR1C3GGPS1CA2PLGF10 | |
| SCHEMBL7695396 | 0.84 | AKR1C3 (0.48) | AKR1C3GGPS1CA2PLGMEN1 | |
| SCHEMBL7791333 | 0.83 | AKR1C3 (0.54) | AKR1C3GGPS1MEN1KMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103720-A | ENZYME INHIBITORS; ANTIICHEMIC AND -TUMOR AGENTS; STROKES; ALZEIMER'S DISEASE | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-15 | — | — | US | disclosed |
| EP-0944582-A1 | KETOBENZAMIDES AS CALPAIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025883-A1 | KETOBENZAMIDES AS CALPAIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-18 | — | — | WO | disclosed |