Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 4/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PKLR | P30613 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6939223 | 1.00 | CAPN1 (0.52) | CAPN1CTSLCTSBPKMPKLR | |
| SCHEMBL7315676 | 0.86 | PKM (0.51) | PKMPKLRMEN1KMT2AALDH1A1 | |
| SCHEMBL7787036 | 0.84 | PKM (0.54) | PKMPKLRMEN1KMT2AALDH1A1 | |
| SCHEMBL7787038 | 0.84 | PKM (0.54) | PKMPKLRMEN1KMT2AALDH1A1 | |
| SCHEMBL6942097 | 0.84 | CAPN1 (0.53) | CAPN1CTSLCTSBMEN1KMT2A | |
| SCHEMBL7313713 | 0.84 | CAPN1 (0.53) | CAPN1CTSLCTSBMEN1KMT2A | |
| SCHEMBL7787019 | 0.84 | CAPN1 (0.53) | CAPN1PKMPKLRMEN1KMT2A | |
| SCHEMBL7787021 | 0.84 | CAPN1 (0.53) | CAPN1PKMPKLRMEN1KMT2A | |
| SCHEMBL7322058 | 0.77 | MEN1 (0.75) | PKMPKLRMEN1KMT2AALDH1A1 | |
| SCHEMBL6799611 | 0.76 | CAPN1 (0.51) | CAPN1CTSLCTSBPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103720-A | ENZYME INHIBITORS; ANTIICHEMIC AND -TUMOR AGENTS; STROKES; ALZEIMER'S DISEASE | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-15 | — | — | US | disclosed |