Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944325 | 1.00 | AKR1C3 (0.48) | AKR1C3GGPS1CA2GPR27KAT6A | |
| SCHEMBL7313713 | 0.87 | CAPN1 (0.53) | AKR1C3GGPS1CA2GPR27KAT6A | |
| SCHEMBL6942097 | 0.87 | CAPN1 (0.53) | AKR1C3GGPS1CA2GPR27KAT6A | |
| SCHEMBL7695396 | 0.84 | AKR1C3 (0.48) | AKR1C3GGPS1CA2GPR27KAT6A | |
| SCHEMBL6947064 | 0.83 | CTSD (0.48) | AKR1C3GGPS1GPR27KAT6ASLC16A3 | |
| SCHEMBL7692550 | 0.83 | AKR1C3 (0.51) | AKR1C3GGPS1CA2GPR27KAT6A | |
| SCHEMBL7694179 | 0.82 | AKR1C3 (0.48) | AKR1C3GGPS1CA2GPR27KAT6A | |
| SCHEMBL7791335 | 0.81 | AKR1C3 (0.54) | AKR1C3GGPS1GPR27KAT6ASLC16A3 | |
| SCHEMBL7791333 | 0.81 | AKR1C3 (0.54) | AKR1C3GGPS1GPR27KAT6ASLC16A3 | |
| SCHEMBL7782218 | 0.80 | AKR1C3 (0.53) | AKR1C3GGPS1GPR27KAT6ASLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944582-B1 | KETOBENZAMIDES AS CALPAIN INHIBITORS | ABBOTT GMBH & CO KG (DE) | 2003-07-02 | — | — | EP | disclosed |
| US-6103720-A | ENZYME INHIBITORS; ANTIICHEMIC AND -TUMOR AGENTS; STROKES; ALZEIMER'S DISEASE | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-15 | — | — | US | disclosed |
| EP-0944582-A1 | KETOBENZAMIDES AS CALPAIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025883-A1 | KETOBENZAMIDES AS CALPAIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-18 | — | — | WO | disclosed |