Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313778 | 0.81 | HTR2A (0.32) | HTR2ASLC6A4PDE3BPDE3A | |
| SCHEMBL7309323 | 0.81 | PDE3B (0.33) | HTR2ASLC6A4PDE3BPDE3A | |
| SCHEMBL7307768 | 0.74 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL7317946 | 0.71 | SLC6A4 (0.33) | HTR2ASLC6A4 | |
| SCHEMBL7309010 | 0.70 | SLC6A4 (0.33) | HTR2ASLC6A4 | |
| SCHEMBL7315005 | 0.69 | REN (0.33) | HTR2ASLC6A4 | |
| SCHEMBL7308468 | 0.66 | PDE3B (0.34) | PDE3BPDE3A | |
| SCHEMBL7309331 | 0.62 | PDE3B (0.35) | HTR2ASLC6A4PDE3BPDE3A | |
| SCHEMBL7312727 | 0.60 | PDE3B (0.48) | PDE3BPDE3A | |
| SCHEMBL7313127 | 0.60 | PDE3B (0.51) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |