Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 9/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309010 | 0.88 | SLC6A4 (0.33) | RENSLC6A4SLC6A2L3MBTL1HTR2A | |
| SCHEMBL7317946 | 0.86 | SLC6A4 (0.33) | RENSLC6A4SLC6A2HTR2ASLC6A3 | |
| SCHEMBL7315018 | 0.80 | REN (0.33) | RENSLC6A4SLC6A2HTR2A | |
| SCHEMBL7316010 | 0.71 | ALDH1A1 (0.36) | RENSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7315012 | 0.70 | KMT2A (0.40) | — | |
| SCHEMBL7313755 | 0.69 | HTR2A (0.31) | SLC6A4HTR2A | |
| SCHEMBL7309323 | 0.69 | PDE3B (0.33) | SLC6A4HTR2A | |
| SCHEMBL7317889 | 0.67 | ALDH1A1 (0.36) | REN | |
| SCHEMBL7309025 | 0.67 | SLC6A4 (0.32) | RENSLC6A4SLC6A2HTR2A | |
| SCHEMBL7320149 | 0.65 | ALDH1A1 (0.35) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |