Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7305120 | 0.99 | KMT2A (0.70) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL7317757 | 0.91 | ADRB2 (0.68) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL7318091 | 0.88 | KMT2A (0.71) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL7317203 | 0.88 | KMT2A (0.65) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL7317835 | 0.87 | KMT2A (0.64) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL7314684 | 0.86 | ADRB2 (0.56) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL7314970 | 0.85 | KMT2A (0.64) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL7320022 | 0.84 | ADRB2 (0.78) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL7317527 | 0.83 | KMT2A (0.67) | KMT2AADRB2ADRB1HTR1AADRA2C | |
| SCHEMBL7317219 | 0.83 | ADRB2 (0.63) | KMT2AADRB2ADRB1HTR1AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258062-A | ISOPRENALINE ANTAGONISTS EFFECTING HEART RATE AND BLOOD PRESSURE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-03-24 | — | — | US | disclosed |
| US-4171370-A | Phenoxy-amino-propanols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-10-16 | — | — | US | disclosed |