Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313778 | 0.82 | HTR2A (0.32) | PDE3BPDE3A | |
| SCHEMBL7309327 | 0.77 | PDE3B (0.38) | HDAC1HDAC6HDAC3HDAC2BRD4 | |
| SCHEMBL7304527 | 0.76 | PDE3B (0.57) | PDE3BPDE3A | |
| SCHEMBL7305746 | 0.73 | PDE3B (0.42) | HDAC1HDAC6HDAC3HDAC2BRD4 | |
| SCHEMBL7307774 | 0.73 | PDE3B (0.60) | PDE3BPDE3A | |
| SCHEMBL7316993 | 0.72 | MAPT (0.34) | HDAC1HDAC3HDAC2PDE3BPDE3A | |
| SCHEMBL7317952 | 0.68 | KMT2A (0.39) | HDAC1HDAC6HDAC3HDAC2BRD4 | |
| SCHEMBL7305263 | 0.68 | PDE3B (0.47) | PDE3BPDE3A | |
| SCHEMBL7309017 | 0.66 | KMT2A (0.41) | HDAC1HDAC6HDAC3HDAC2BRD4 | |
| SCHEMBL7315012 | 0.66 | KMT2A (0.40) | HDAC1HDAC6HDAC3HDAC2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |