Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309017 | 0.86 | KMT2A (0.41) | KMT2AALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL7317952 | 0.84 | KMT2A (0.39) | KMT2AALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL7315018 | 0.79 | REN (0.33) | — | |
| SCHEMBL7310467 | 0.73 | ALDH1A1 (0.48) | KMT2AALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL7312384 | 0.71 | CNR1 (0.42) | KMT2AALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL7316021 | 0.70 | ALDH1A1 (0.49) | KMT2AALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL7315005 | 0.70 | REN (0.33) | — | |
| SCHEMBL7309450 | 0.68 | MAPT (0.52) | KMT2AALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL7314458 | 0.67 | ALDH1A1 (0.36) | KMT2AALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL7320203 | 0.67 | CNR1 (0.42) | KMT2AALDH1A1POLBKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |