Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | CMA1 | P23946 | 9/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 2/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.50 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315995 | 0.97 | ITGB3 (0.62) | ITGB3ITGA2BCMA1F2PRSS1 | |
| SCHEMBL7321341 | 0.95 | CMA1 (0.56) | ITGB3ITGA2BCMA1F2PRSS1 | |
| Sulfurous Acid SCHEMBL7322037 | 0.94 | ITGB3 (0.59) | ITGB3ITGA2BCMA1F2PRSS1 | |
| SCHEMBL7321824 | 0.90 | ITGB3 (0.59) | ITGB3ITGA2BCMA1F2PRSS1 | |
| SCHEMBL7322422 | 0.89 | ITGB3 (0.64) | ITGB3ITGA2BCMA1KLK7KLK5 | |
| SCHEMBL7324440 | 0.89 | MALT1 (0.59) | ITGB3ITGA2BCMA1MALT1 | |
| SCHEMBL10800056 | 0.88 | ITGB3 (0.63) | ITGB3ITGA2BCMA1F2PRSS1 | |
| SCHEMBL7325125 | 0.88 | ITGB3 (0.62) | ITGB3ITGA2BCMA1KLK7KLK5 | |
| SCHEMBL7312909 | 0.87 | ITGB3 (0.62) | ITGB3ITGA2BCMA1F2PRSS1 | |
| SCHEMBL7314754 | 0.87 | MALT1 (0.53) | ITGB3ITGA2BCMA1MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4691007-A | HUMAN LEUKOCYTE ELASTASE INHIBITORS | ICI AMERICAS INC. (US) | 1987-09-01 | — | — | US | disclosed |
| US-4596789-A | Pharmaceuticals | ICI AMERICAS INC. (US) | 1986-06-24 | — | — | US | disclosed |
| EP-0124317-A2 | Proline derivatives | ICI AMERICAS INC. (US) | 1984-11-07 | — | — | EP | disclosed |