Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.62 |
| ▸ | CMA1 | P23946 | 11/20 | 0.53 |
| ▸ | KLK7 | P49862 | 2/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.51 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321824 | 0.97 | ITGB3 (0.59) | ITGB3ITGA2BCMA1KLK7KLK5 | |
| SCHEMBL7320222 | 0.93 | CMA1 (0.56) | ITGB3ITGA2BCMA1KLK7KLK5 | |
| SCHEMBL10800056 | 0.91 | ITGB3 (0.63) | ITGB3ITGA2BCMA1KLK7KLK5 | |
| SCHEMBL7315995 | 0.90 | ITGB3 (0.62) | ITGB3ITGA2BCMA1KLK7KLK5 | |
| SCHEMBL7322145 | 0.89 | ITGB3 (0.67) | ITGB3ITGA2BCMA1KLK7KLK5 | |
| SCHEMBL5971737 | 0.88 | ITGB3 (0.66) | ITGB3ITGA2BCMA1KLK7KLK5 | |
| SCHEMBL7314317 | 0.87 | ITGB3 (0.59) | ITGB3ITGA2BCMA1KLK7KLK5 | |
| Sulfurous Acid SCHEMBL7322037 | 0.87 | ITGB3 (0.59) | ITGB3ITGA2BCMA1KLK7KLK5 | |
| SCHEMBL7321814 | 0.87 | ITGB3 (0.65) | ITGB3ITGA2BCMA1KLK7KLK5 | |
| SCHEMBL7322422 | 0.86 | ITGB3 (0.64) | ITGB3ITGA2BCMA1KLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124317-A2 | Proline derivatives | ICI AMERICAS INC. (US) | 1984-11-07 | — | — | EP | disclosed |