Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310988 | 0.94 | HTR2B (0.52) | HTR2BMEN1LMNAMAPTKMT2A | |
| SCHEMBL7303482 | 0.89 | HTR2B (0.48) | HTR2BLMNACYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL7314554 | 0.89 | HTR2B (0.45) | HTR2BMEN1LMNAMAPTKMT2A | |
| SCHEMBL7308689 | 0.87 | HTR2B (0.54) | HTR2BMEN1LMNAMAPTKMT2A | |
| SCHEMBL7303829 | 0.84 | HTR2B (0.47) | HTR2BSMN1; SMN2PARP1PARP2HTR4 | |
| SCHEMBL7314575 | 0.83 | HTR2B (0.44) | HTR2BCYP1A2MAPK1SMN1; SMN2MAOB | |
| SCHEMBL7309134 | 0.83 | HTR2B (0.39) | HTR2BMEN1LMNAMAPTKMT2A | |
| SCHEMBL7306985 | 0.82 | HTR2B (0.44) | HTR2BCYP1A2MAPK1SMN1; SMN2MAOA | |
| SCHEMBL7305444 | 0.82 | HTR2B (0.50) | HTR2BCCR5MAOAHSD17B10 | |
| SCHEMBL7306400 | 0.81 | HTR2B (0.53) | HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |