Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 2/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303829 | 0.94 | HTR2B (0.47) | HTR2BITGB3ITGA2BSMN1; SMN2OPRM1 | |
| SCHEMBL7311014 | 0.90 | HTR2B (0.43) | HTR2BHSD17B10ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL7314426 | 0.89 | HTR2B (0.50) | HTR2BHSD17B10SMN1; SMN2MAOAHTR4 | |
| SCHEMBL7302525 | 0.88 | HTR2B (0.48) | HTR2BITGB3ITGA2BOPRM1OPRD1 | |
| SCHEMBL7310988 | 0.85 | HTR2B (0.52) | HTR2BCCR2KCNH2HTR4MEN1 | |
| SCHEMBL7310324 | 0.85 | HTR2B (0.40) | HTR2BHSD17B10ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL7313291 | 0.84 | HTR2B (0.40) | HTR2BITGB3ITGA2BSMN1; SMN2MAOA | |
| SCHEMBL7305668 | 0.84 | HTR2B (0.36) | HTR2BITGB3ITGA2BMAOACCR2 | |
| SCHEMBL7311678 | 0.83 | HTR2B (0.45) | HTR2BHSD17B10ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL7306441 | 0.82 | HTR2B (0.48) | HTR2BOPRM1OPRD1CCR8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |