Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316132 | 0.87 | ALDH1A1 (0.36) | ALDH1A1KDM4EMAPTCYP2D6CYP2C19 | |
| SCHEMBL7310850 | 0.86 | ALDH1A1 (0.36) | ALDH1A1KDM4EMAPTCYP2D6CYP2C19 | |
| SCHEMBL7319891 | 0.84 | KDM4E (0.37) | ALDH1A1KDM4EMAPTCYP2D6CYP2C19 | |
| SCHEMBL7309666 | 0.79 | KDM4E (0.38) | ALDH1A1KDM4EMAPTCYP2D6CYP2C19 | |
| SCHEMBL7311336 | 0.78 | SIRT3 (0.36) | ALDH1A1KDM4EMAPTCYP2D6CYP2C19 | |
| SCHEMBL7306833 | 0.77 | ALDH1A1 (0.37) | ALDH1A1KDM4EMAPTCYP2D6CYP2C19 | |
| SCHEMBL10377113 | 0.77 | ALDH1A1 (0.37) | ALDH1A1KDM4EMAPTCYP2D6CYP2C19 | |
| SCHEMBL7316430 | 0.75 | SMN1; SMN2 (0.42) | ALDH1A1KDM4EMAPTGAALMNA | |
| SCHEMBL10374618 | 0.75 | ALDH1A1 (0.37) | ALDH1A1MAPTCYP2D6CYP2C19GAA | |
| SCHEMBL10375872 | 0.74 | ALDH1A1 (0.36) | ALDH1A1KDM4EMAPTCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |