Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312566 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL7307518 | 0.84 | KMT2A (0.43) | SMN1; SMN2ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL7316434 | 0.76 | MAPT (0.35) | SMN1; SMN2ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL7314458 | 0.75 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL7311336 | 0.74 | SIRT3 (0.36) | SMN1; SMN2ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL10374595 | 0.73 | LMNA (0.45) | SMN1; SMN2ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL10376143 | 0.71 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL7319891 | 0.70 | KDM4E (0.37) | SMN1; SMN2ALDH1A1KMT2APOLBGAA | |
| SCHEMBL7345715 | 0.68 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL7309468 | 0.67 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |