Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305713 | 0.98 | ITGB3 (0.37) | ITGB3ITGA2BALDH1A1L3MBTL1MEN1 | |
| SCHEMBL7308973 | 0.95 | ITGB3 (0.38) | ITGB3ITGA2BMEN1KMT2AKDM4E | |
| SCHEMBL7316892 | 0.91 | ITGB3 (0.37) | ITGB3ITGA2BALDH1A1L3MBTL1MEN1 | |
| SCHEMBL7310379 | 0.90 | ITGB3 (0.37) | ITGB3ITGA2BALDH1A1L3MBTL1MEN1 | |
| SCHEMBL7307496 | 0.90 | KCNH2 (0.36) | ITGB3ITGA2BALDH1A1MEN1KMT2A | |
| SCHEMBL7304312 | 0.89 | KCNH2 (0.34) | ITGB3ITGA2BALDH1A1MEN1KMT2A | |
| SCHEMBL7316734 | 0.88 | KCNH2 (0.37) | ITGB3ITGA2BALDH1A1MEN1KMT2A | |
| SCHEMBL7314406 | 0.87 | ITGB3 (0.36) | ITGB3ITGA2BALDH1A1L3MBTL1MEN1 | |
| SCHEMBL7306954 | 0.86 | KCNH2 (0.37) | ITGB3ITGA2BMEN1KMT2APOLB | |
| SCHEMBL7311904 | 0.86 | ITGB3 (0.32) | ITGB3ITGA2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |