Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 4/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 9/20 | 0.32 |
| ▸ | CNR1 | P21554 | 9/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317183 | 0.84 | PDE3B (0.59) | PDE3BPDE3A | |
| SCHEMBL7315274 | 0.82 | PDE3B (0.45) | PDE3BPDE3ACNR2CNR1 | |
| SCHEMBL7314546 | 0.72 | PDE3B (0.39) | PDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL7313625 | 0.71 | SMN1; SMN2 (0.37) | CNR2CNR1SMN1; SMN2 | |
| SCHEMBL7317420 | 0.71 | CNR1 (0.36) | CNR2CNR1SMN1; SMN2 | |
| SCHEMBL7316821 | 0.71 | PDE3B (0.57) | PDE3BPDE3A | |
| SCHEMBL7316827 | 0.71 | PDE3B (0.57) | PDE3BPDE3A | |
| SCHEMBL7319250 | 0.70 | SIRT3 (0.38) | CNR2CNR1 | |
| SCHEMBL7308462 | 0.69 | PDE3B (0.36) | PDE3BPDE3ACNR2CNR1HDAC1 | |
| SCHEMBL10374576 | 0.68 | PDE3B (0.69) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |