SCHEMBL7315274

SCHEMBL7315274

Cc1cc(OCCCCCCC(=O)NC2CCc3ccccc3N2)cc2c1CN1C(=N2)NC(=O)C1CO

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 17/20 0.45
PDE3A Q14432 17/20 0.45
CNR2 P34972 2/20 0.32
CNR1 P21554 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7308799 0.85 PDE3B (0.60) PDE3BPDE3A
SCHEMBL7314537 0.82 PDE3B (0.43) PDE3BPDE3ACNR2CNR1
SCHEMBL7315285 0.73 PDE3B (0.41) PDE3BPDE3A
SCHEMBL10374576 0.72 PDE3B (0.69) PDE3BPDE3A
SCHEMBL7313625 0.71 SMN1; SMN2 (0.37) CNR2CNR1
SCHEMBL7317420 0.71 CNR1 (0.36) CNR2CNR1
SCHEMBL7310481 0.71 PDE3B (0.59) PDE3BPDE3A
SCHEMBL7310474 0.71 PDE3B (0.58) PDE3BPDE3A
SCHEMBL7321172 0.69 PDE3B (0.38) PDE3BPDE3ACNR2CNR1
SCHEMBL7313434 0.68 PDE3B (0.58) PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670434-A ANTICOAGULANT, INOTROPIC AGENT SYNTEX (U.S.A.) INC. (US) 1987-06-02 US disclosed