Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320826 | 0.82 | PDE3B (0.56) | PDE3BPDE3ASMN1; SMN2 | |
| SCHEMBL7308468 | 0.81 | PDE3B (0.34) | PDE3BPDE3A | |
| SCHEMBL7321172 | 0.80 | PDE3B (0.38) | PDE3BPDE3AMEN1KMT2ACNR1 | |
| SCHEMBL7310172 | 0.69 | DRD2 (0.41) | MEN1KMT2ACNR1CNR2DRD2 | |
| SCHEMBL7317796 | 0.69 | PDE3B (0.69) | PDE3BPDE3A | |
| SCHEMBL7318574 | 0.69 | MEN1 (0.41) | MEN1KMT2ACNR1CNR2DRD2 | |
| SCHEMBL7314537 | 0.69 | PDE3B (0.43) | PDE3BPDE3ACNR1CNR2HDAC1 | |
| SCHEMBL7312977 | 0.68 | SIRT3 (0.43) | MEN1KMT2ACNR1CNR2HTR1A | |
| SCHEMBL7313946 | 0.67 | PDE3B (0.52) | PDE3BPDE3A | |
| SCHEMBL7316751 | 0.66 | PDE3B (0.45) | PDE3BPDE3AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |