Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 18/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538989 | 0.79 | SCN9A (0.47) | SLC6A3SCN9ASLC6A2SLC6A4 | |
| SCHEMBL7534451 | 0.79 | EDNRA (0.48) | SLC6A3SCN9A | |
| SCHEMBL4597267 | 0.77 | POLB (0.55) | SCN9A | |
| SCHEMBL30281291 | 0.74 | PDK2 (0.50) | — | |
| SCHEMBL19039047 | 0.74 | PDK2 (0.50) | — | |
| SCHEMBL4730463 | 0.74 | SCN9A (0.45) | SLC6A3SCN9A | |
| SCHEMBL14970793 | 0.73 | SLC6A2 (0.43) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL23996970 | 0.73 | PDK2 (0.45) | — | |
| SCHEMBL18450888 | 0.73 | LMNA (0.38) | — | |
| SCHEMBL11609817 | 0.71 | SLC6A3 (0.56) | SLC6A3SCN9ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |
| WO-1999041227-A1 | TRICYCLIC COMPOUNDS AS GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-08-19 | — | — | WO | disclosed |