Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326089 | 0.83 | TSHR (0.42) | LMNAGAACTNNB1WNT3AKDM4E | |
| SCHEMBL10376092 | 0.80 | TSHR (0.47) | LMNAGAACTNNB1WNT3AKDM4E | |
| SCHEMBL7321849 | 0.79 | SLC6A2 (0.39) | SLC6A2SLC6A4CYP2C9CYP2C19HTR2B | |
| SCHEMBL7316268 | 0.76 | LMNA (0.47) | CNR2LMNAGAACTNNB1WNT3A | |
| SCHEMBL7314068 | 0.75 | NFKB1 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4SLC6A2 | |
| SCHEMBL7314062 | 0.75 | NFKB1 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4SLC6A2 | |
| SCHEMBL7314178 | 0.71 | APP (0.46) | CHRM5KDM4ETTR | |
| SCHEMBL7314074 | 0.71 | MEN1 (0.37) | HTR2B | |
| SCHEMBL15482714 | 0.70 | LMNA (0.31) | LMNA | |
| SCHEMBL29579976 | 0.68 | LMNA (0.60) | CNR2LMNAGAACTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217142-A2 | A polyazaheterocyclic compound | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1987-04-08 | — | — | EP | disclosed |