Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 15/20 | 0.45 |
| ▸ | MMP13 | P45452 | 14/20 | 0.45 |
| ▸ | MMP1 | P03956 | 11/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 9/20 | 0.45 |
| ▸ | BMP1 | P13497 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 6/20 | 0.40 |
| ▸ | MMP12 | P39900 | 6/20 | 0.40 |
| ▸ | MMP8 | P22894 | 5/20 | 0.40 |
| ▸ | MMP14 | P50281 | 5/20 | 0.40 |
| ▸ | MMP16 | P51512 | 5/20 | 0.40 |
| ▸ | MMP3 | P08254 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321346 | 0.93 | ACP1 (0.39) | MMP9MMP13MMP1ADAM17BMP1 | |
| Hydrochloric Acid SCHEMBL7323688 | 0.87 | MMP13 (0.51) | MMP9MMP13MMP1ADAM17MMP2 | |
| Hydrochloric Acid SCHEMBL7319131 | 0.87 | MMP9 (0.47) | MMP9MMP13MMP1ADAM17MMP2 | |
| Hydrochloric Acid SCHEMBL7320375 | 0.86 | MMP9 (0.58) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7317079 | 0.86 | MMP13 (0.40) | MMP9MMP13MMP1ADAM17MMP2 | |
| Hydrochloric Acid SCHEMBL7323789 | 0.86 | MMP9 (0.47) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7321745 | 0.85 | MMP13 (0.49) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7322582 | 0.84 | MMP9 (0.52) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7310011 | 0.83 | MMP13 (0.51) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL7322248 | 0.83 | MMP13 (0.43) | MMP9MMP13MMP1ADAM17MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |