Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 19/20 | 0.53 |
| ▸ | MMP13 | P45452 | 19/20 | 0.53 |
| ▸ | MMP1 | P03956 | 18/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 17/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7320381 | 0.94 | MMP9 (0.52) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7321365 | 0.92 | MMP9 (0.45) | MMP9MMP13MMP1ADAM17 | |
| Hydrochloric Acid SCHEMBL7323698 | 0.88 | MMP9 (0.52) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7317089 | 0.87 | MMP9 (0.48) | MMP9MMP13MMP1ADAM17 | |
| Hydrochloric Acid SCHEMBL7323801 | 0.85 | MMP9 (0.48) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7324189 | 0.85 | MMP9 (0.48) | MMP9MMP13MMP1ADAM17 | |
| Hydrochloric Acid SCHEMBL7318232 | 0.85 | MMP9 (0.48) | MMP9MMP13MMP1ADAM17 | |
| Hydrochloric Acid SCHEMBL7319142 | 0.85 | MMP9 (0.51) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7313293 | 0.83 | MMP1 (0.43) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7317369 | 0.82 | MMP9 (0.43) | MMP9MMP13MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |