Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC33A1 | O00400 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313030 | 0.94 | — | — | |
| Morpholine SCHEMBL7319945 | 0.88 | HTR2A (0.41) | SLC33A1 | |
| Pyrrolidine SCHEMBL7313042 | 0.84 | HTR2A (0.41) | — | |
| SCHEMBL7313123 | 0.84 | ALDH1A1 (0.46) | KDM4ENPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7317120 | 0.84 | SLC33A1 (0.40) | SLC33A1 | |
| SCHEMBL7315139 | 0.81 | — | — | |
| SCHEMBL9260598 | 0.81 | SLC33A1 (0.45) | SLC33A1 | |
| SCHEMBL7320487 | 0.80 | AGTR1 (0.41) | — | |
| SCHEMBL7319381 | 0.80 | — | — | |
| SCHEMBL9258772 | 0.79 | SLC33A1 (0.44) | SLC33A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389632-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1995-02-14 | — | — | US | disclosed |
| US-5231094-A | Cardiovascular disorders | SOCIETE ANONYME: LABORATOIRES UPSA (FR) | 1993-07-27 | — | — | US | disclosed |