Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 18/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310741 | 0.85 | CHRM2 (0.30) | KCNH2CHRM2CHRM1CHRM3 | |
| SCHEMBL7317382 | 0.82 | — | — | |
| SCHEMBL8083545 | 0.82 | EBP (0.39) | KCNH2CACNA1CCHRM2 | |
| SCHEMBL7308385 | 0.82 | EBP (0.39) | KCNH2CACNA1CCHRM2 | |
| SCHEMBL7305146 | 0.82 | — | — | |
| SCHEMBL7315451 | 0.79 | PTGER4 (0.30) | — | |
| SCHEMBL7315081 | 0.78 | — | — | |
| SCHEMBL7318716 | 0.78 | — | — | |
| SCHEMBL7309070 | 0.75 | EBP (0.39) | — | |
| SCHEMBL7314199 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |