Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305146 | 0.92 | — | — | |
| SCHEMBL7314910 | 0.85 | CACNA1G (0.38) | CHRM2CHRM3KCNH2CHRM1 | |
| SCHEMBL7315451 | 0.85 | PTGER4 (0.30) | — | |
| SCHEMBL7317382 | 0.82 | — | — | |
| SCHEMBL8083545 | 0.82 | EBP (0.39) | CHRM2LMNACYP2D6KCNH2CYP2C19 | |
| SCHEMBL7308385 | 0.82 | EBP (0.39) | CHRM2LMNACYP2D6KCNH2CYP2C19 | |
| SCHEMBL7315081 | 0.77 | — | — | |
| SCHEMBL7318716 | 0.77 | — | — | |
| SCHEMBL7314199 | 0.76 | — | — | |
| SCHEMBL7319271 | 0.76 | SLC22A2 (0.35) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |