Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 18/20 | 0.78 |
| ▸ | MMP13 | P45452 | 18/20 | 0.78 |
| ▸ | MMP1 | P03956 | 17/20 | 0.78 |
| ▸ | ADAM17 | P78536 | 8/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443729 | 0.88 | MMP13 (1.00) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7323902 | 0.88 | MMP13 (1.00) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7322084 | 0.86 | MMP13 (0.82) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7325101 | 0.85 | MMP13 (0.84) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7973905 | 0.83 | MMP13 (0.83) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7311378 | 0.82 | MMP13 (1.00) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL5163025 | 0.82 | MMP13 (0.75) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL6129930 | 0.81 | MMP9 (1.00) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7313705 | 0.80 | MMP13 (0.74) | MMP9MMP13MMP1ADAM17 | |
| SCHEMBL7323348 | 0.79 | MMP9 (1.00) | MMP9MMP13MMP1ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |