Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315345 | 0.81 | ITGB3 (0.55) | ITGB3ITGA2B | |
| SCHEMBL7315330 | 0.81 | ITGB3 (0.55) | ITGB3ITGA2B | |
| SCHEMBL7295572 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2BDPP4DPP8 | |
| SCHEMBL7295577 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2BDPP4DPP8 | |
| SCHEMBL7295570 | 0.79 | ITGB3 (0.47) | ITGB3ITGA2BDPP4DPP8 | |
| SCHEMBL8548220 | 0.77 | ITGB3 (0.50) | ITGB3ITGA2BDPP4DPP8 | |
| SCHEMBL8548212 | 0.77 | ITGB3 (0.50) | ITGB3ITGA2BDPP4DPP8 | |
| SCHEMBL7309996 | 0.73 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL7295388 | 0.73 | ITGB3 (0.50) | ITGB3ITGA2B | |
| SCHEMBL8553717 | 0.72 | ITGB3 (0.51) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950658-A1 | 2-Pipirazinone-1-acetic acid dihydrochloride derivative used to inhibit platelet aggregation | Takeda Chemical Industries, Ltd. (JP) | 1999-10-20 | — | — | EP | disclosed |