Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.50 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548220 | 1.00 | ITGB3 (0.50) | ITGB3ITGA2BITGAVP2RX7DPP4 | |
| SCHEMBL7295572 | 0.93 | ITGB3 (0.47) | ITGB3ITGA2BP2RX7DPP4DPP8 | |
| SCHEMBL7295577 | 0.93 | ITGB3 (0.47) | ITGB3ITGA2BP2RX7DPP4DPP8 | |
| SCHEMBL7295570 | 0.93 | ITGB3 (0.47) | ITGB3ITGA2BP2RX7DPP4DPP8 | |
| SCHEMBL7287954 | 0.84 | ITGB3 (0.43) | ITGB3ITGA2BITGAVP2RX7CTSK | |
| SCHEMBL7287967 | 0.84 | ITGB3 (0.43) | ITGB3ITGA2BITGAVP2RX7CTSK | |
| SCHEMBL7287962 | 0.84 | ITGB3 (0.43) | ITGB3ITGA2BITGAVP2RX7CTSK | |
| SCHEMBL7308737 | 0.81 | P2RX7 (0.47) | ITGB3ITGA2BP2RX7CTSKCTSB | |
| SCHEMBL8355654 | 0.80 | ITGB3 (0.47) | ITGB3ITGA2BP2RX7DPP4DPP8 | |
| Hydrochloric Acid SCHEMBL8553377 | 0.79 | P2RX7 (0.41) | ITGB3ITGA2BP2RX7CTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822931-A1 | PIPERAZINONES USEFUL AS INHIBITORS OF PLATELET AGGREGATION | Takeda Chemical Industries, Ltd. (JP) | 1998-02-11 | — | — | EP | disclosed |