Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS11D | O60235 | 15/20 | 0.51 |
| ▸ | F2 | P00734 | 9/20 | 0.49 |
| ▸ | F10 | P00742 | 4/20 | 0.49 |
| ▸ | PLG | P00747 | 4/20 | 0.49 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7944779 | 0.99 | TMPRSS11D (0.50) | TMPRSS11DF2F10PLGTMPRSS6 | |
| SCHEMBL7393489 | 0.86 | PROC (0.57) | F2F10TMPRSS6 | |
| Hydrochloric Acid SCHEMBL7951695 | 0.85 | PROC (0.56) | F2F10TMPRSS6 | |
| SCHEMBL7316950 | 0.85 | F2 (0.51) | F2 | |
| Hydrochloric Acid SCHEMBL7953121 | 0.84 | F2 (0.52) | F2PLG | |
| SCHEMBL7311919 | 0.80 | TPSAB1 (0.48) | F2F10 | |
| Hydrochloric Acid SCHEMBL7955507 | 0.80 | TPSAB1 (0.48) | F2F10 | |
| SCHEMBL7306531 | 0.76 | PROC (0.55) | F2F10 | |
| Hydrochloric Acid SCHEMBL7953794 | 0.75 | PROC (0.55) | F2F10 | |
| Hydrochloric Acid SCHEMBL7951566 | 0.75 | PROC (0.55) | F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050534-B1 | 2,3-methano-amino acid derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2001-12-05 | — | — | EP | disclosed |
| US-6288077-B1 | 2-AZABICYCLO(3.1.0)HEXANE-1,2-DICARBOXYLIC AMIDE OR 2-AZABICYCLO(4.1.0)HEPTANE-1,2-DICARBOXYLIC AMIDE DERIVATIVE; TRYPSIN-LIKE SERINE PROTEASE INHIBITOR; ANTICOAGULANTS | ADIR ET COMPAGNIE (FR) | 2001-09-11 | — | — | US | disclosed |
| EP-1050534-A1 | 2,3-methano-amino acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-11-08 | — | — | EP | disclosed |