Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.51 |
| ▸ | PROC | P04070 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7953121 | 0.99 | F2 (0.52) | F2PROCTPSAB1DPP4F7 | |
| SCHEMBL7311919 | 0.88 | TPSAB1 (0.48) | F2PROCTPSAB1 | |
| Hydrochloric Acid SCHEMBL7955507 | 0.87 | TPSAB1 (0.48) | F2PROCTPSAB1F7 | |
| SCHEMBL7393489 | 0.87 | PROC (0.57) | F2PROCF7 | |
| Hydrochloric Acid SCHEMBL7951695 | 0.86 | PROC (0.56) | F2PROCF7 | |
| SCHEMBL7307083 | 0.86 | F2 (0.50) | F2PROCTPSAB1 | |
| Hydrochloric Acid SCHEMBL7951637 | 0.85 | F2 (0.51) | F2PROCTPSAB1 | |
| SCHEMBL7315371 | 0.85 | TMPRSS11D (0.51) | F2 | |
| SCHEMBL7304476 | 0.84 | F2 (0.47) | F2PROCTPSAB1 | |
| Hydrochloric Acid SCHEMBL7944779 | 0.84 | TMPRSS11D (0.50) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050534-B1 | 2,3-methano-amino acid derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2001-12-05 | — | — | EP | disclosed |
| EP-1050534-A1 | 2,3-methano-amino acid derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-11-08 | — | — | EP | disclosed |