Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412752 | 0.95 | LOXL2 (0.59) | LOXL2MAPTSMN1; SMN2RAB9ANPC1 | |
| Biphenyl Dimethyl Dicarboxylate SCHEMBL2890575 | 0.88 | CA1 (0.56) | LOXL2MAPTMEN1KMT2ACA1 | |
| SCHEMBL6665979 | 0.86 | LOXL2 (0.66) | LOXL2MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL14926515 | 0.84 | LOXL2 (0.59) | LOXL2MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10243318 | 0.84 | LOXL2 (0.63) | LOXL2MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10243185 | 0.84 | LOXL2 (0.63) | LOXL2MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7317105 | 0.84 | MAPT (0.53) | LOXL2MAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL13266929 | 0.83 | RARB (0.57) | MAPTSMN1; SMN2RAB9ANPC1MEN1 | |
| Ether SCHEMBL22720575 | 0.82 | CA1 (0.61) | LOXL2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL7218133 | 0.81 | LOXL2 (0.56) | LOXL2MAPTSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |