SCHEMBL73154

SCHEMBL73154

CCCCCCCCCCCCCCCCCCC(C(=O)[O-])([N+](C)(C)C)S(=O)(=O)O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.36
CES1 P23141 3/20 0.35
EPHX1 P07099 1/20 0.35
GGPS1 O95749 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL447524 1.00 CES2 (0.36) CES2CES1EPHX1GGPS1
SCHEMBL905454 1.00 CES2 (0.36) CES2CES1EPHX1GGPS1
SCHEMBL3402212 1.00 CES2 (0.36) CES2CES1EPHX1GGPS1
SCHEMBL905462 1.00 CES2 (0.36) CES2CES1EPHX1GGPS1
SCHEMBL3185089 1.00 CES2 (0.36) CES2CES1EPHX1GGPS1
SCHEMBL1017329 0.98 CES2 (0.33) CES2CES1EPHX1
SCHEMBL6243940 0.93 MEN1 (0.33) CES2CES1EPHX1
SCHEMBL8490429 0.87 BBOX1 (0.44)
SCHEMBL8495180 0.87 BBOX1 (0.44)
SCHEMBL8494318 0.87 BBOX1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1575 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118215507-A Lyophilized ENPP1 polypeptide formulations and uses thereof 依诺兹梅制药公司 2024-06-18 CN claimed
US-11998584-B2 Conjugate of a tubulysin analog with branched linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2024-06-04 US claimed
EP-3782550-B1 ZWITTERION SURFACE MODIFICATIONS FOR CONTINUOUS SENSORS DEXCOM INC (US) 2023-12-27 EP claimed
EP-3397398-B1 BIOINTERFACE LAYER FOR ANALYTE SENSORS DEXCOM INC (US) 2023-11-08 EP claimed
EP-3397162-B1 MEMBRANE LAYERS FOR ANALYTE SENSORS DEXCOM INC (US) 2023-09-06 EP claimed
US-20230165931-A1 A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-06-01 US claimed
WO-2023078021-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 WO claimed
WO-2023078273-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 WO claimed
US-20230115871-A1 A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS HANGZHOU DAC BIOTECH CO., LTD (CN) 2023-04-13 US claimed
WO-2023049864-A1 LYOPHILIZED ENPP1 POLYPEPTIDE FORMULATIONS AND USES THEREOF INOZYME PHARMA, INC. (US) 2023-03-30 WO claimed
WO-2018116198-A1 IMPROVED METHODS FOR ENHANCING ANTIBODY PRODUCTIVITY IN MAMMALIAN CELL CULTURE AND MINIMIZING AGGREGATION DURING DOWNSTREAM, FORMULATION PROCESSES AND STABLE ANTIBODY FORMULATIONS OBTAINED THEREOF SERUM INSTITUTE OF INDIA PRIVATE LIMITED (IN) 2018-06-28 WO claimed
US-20180000932-A1 FORMULATION OF AGLYCOSYLATED THERAPEUTIC ANTIBODIES NOVELMED THERAPEUTICS INC (US) 2018-01-04 US claimed
EP-3240571-A1 FORMULATION OF AGLYCOSYLATED THERAPEUTIC ANTIBODIES NovelMed Therapeutics, Inc. (US) 2017-11-08 EP claimed
EP-2585105-B1 TREATMENT OF SANFILIPPO SYNDROME TYPE B SHIRE HUMAN GENETIC THERAPIES (US) 2017-08-09 EP claimed
EP-3048899-A2 ON-COLUMN VIRAL INACTIVATION METHODS Biogen MA Inc. (US) 2016-08-03 EP claimed
WO-2016109822-A1 FORMULATION OF AGLYCOSYLATED THERAPEUTIC ANTIBODIES NOVELMED THERAPEUTICS, INC. (US) 2016-07-07 WO claimed
WO-2015048330-A2 ON-COLUMN VIRAL INACTIVATION METHODS BIOGEN IDEC MA INC. (US) 2015-04-02 WO claimed
US-20100151451-A1 Method for Identifying the Genotype in Position 171 of the Ovine Prion Protein as well as Kits for Implementing said Method BIO-RAD PASTEUR (FR) 2010-06-17 US claimed
EP-1952153-A2 METHOD FOR IDENTIFYING THE GENOTYPE IN POSITION 171 OF THE OVINE PRION PROTEIN AS WELL AS KITS FOR IMPLEMENTING SAID METHOD Bio-Rad Pasteur (FR) 2008-08-06 EP claimed
WO-2007060373-A2 METHOD FOR IDENTIFYING THE GENOTYPE IN POSITION 171 OF THE SHEEP PRION PROTEIN AS WELL AS KITS FOR IMPLEMENTING SAID METHOD BIO-RAD PASTEUR (FR) 2007-05-31 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165931-A1 A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS TEKT1, CD2BP2, CD4 CES2 4727/4885CES1 3979/4885EPHX1 3794/4885
US-11998584-B2 Conjugate of a tubulysin analog with branched linkers TEKT1, TEK, CD2BP2 CES2 4747/4885CES1 4088/4885EPHX1 3619/4885
US-20230115871-A1 A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS CD2BP2, EPCAM, CD74 CES2 1277/4885CES1 2149/4885EPHX1 2649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.