Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL8693555 | 0.98 | CYP2D6 (0.53) | CYP2D6CYP2C9CYP2C19SLC1A3SLC1A2 | |
| SCHEMBL6934209 | 0.84 | ALDH1A1 (0.57) | CYP2D6CYP2C9CYP2C19SLC1A3SLC1A2 | |
| SCHEMBL10718657 | 0.84 | CYP2D6 (0.53) | CYP2D6CYP2C9CYP2C19SLC1A3SLC1A2 | |
| SCHEMBL8692307 | 0.83 | CYP2D6 (0.56) | CYP2D6CYP2C9CYP2C19SLC1A3SLC1A2 | |
| SCHEMBL5898644 | 0.82 | CYP2D6 (0.51) | CYP2D6CYP2C9CYP2C19SLC1A3SLC1A2 | |
| SCHEMBL14417207 | 0.81 | CYP2D6 (0.55) | CYP2D6CYP2C9CYP2C19SLC1A3SLC1A2 | |
| SCHEMBL18112599 | 0.79 | HDAC1 (0.56) | CYP2D6CYP2C9CYP2C19SLC1A3SLC1A2 | |
| SCHEMBL8853840 | 0.79 | CYP2D6 (0.51) | CYP2D6CYP2C9CYP2C19SLC1A3SLC1A2 | |
| SCHEMBL25518523 | 0.79 | CYP2D6 (0.51) | CYP2D6CYP2C9CYP2C19SLC1A3SLC1A2 | |
| SCHEMBL8337692 | 0.77 | CYP2C9 (0.64) | CYP2D6CYP2C9CYP2C19ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035755-A1 | METHOD OF CONTROLLING WEEDS IN A TURF GRASS BY USING SULFONYLUREA COMPOUNDS | MOGHU RESEARCH CENTER LTD. (KR) | 2010-02-11 | — | — | US | claimed |
| EP-1227725-B1 | NON-AQUEOUS OR HARDLY AQUEOUS SUSPENSION CONCENTRATES OF ACTIVE SUBSTANCE COMBINATIONS USED FOR PLANT PROTECTION | BAYER CROPSCIENCE GMBH (DE) | 2004-04-14 | — | — | EP | claimed |
| EP-0729954-B1 | Substituted thiophene sulfonyl ureas and thioureas, process for their preparation, their use as medicaments | HOECHST AG (DE) | 2003-09-03 | — | — | EP | claimed |
| EP-1008297-B1 | Mixtures of herbicides and antidotes | BAYER CROPSCIENCE GMBH (DE) | 2003-03-19 | — | — | EP | claimed |
| US-6479432-B1 | STORAGE-STABLE NON-AQUEOUS OR LOW-WATER SUSPENSION CONCENTRATES IN THE FORM OF SUSPENSIONS WHICH COMPRISE AT LEAST ONE SOLID, SPECIFICALLY FROM THE GROUP OF THE HERBICIDAL SULFONYLUREAS | AVENTIS CROPSCIENCE GMBH (DE) | 2002-11-12 | — | — | US | claimed |
| CN-1071752-C | Substituted thiophenesulfonylureas and-thioureas, processes for their preparation, their use as medicament or diagnostic, and medicament containing them | HOECHST AG (DE) | 2001-09-26 | — | — | CN | claimed |
| EP-0492367-B1 | Mixtures of herbicides and antidotes | AVENTIS CROPSCIENCE GMBH (DE) | 2000-09-27 | — | — | EP | claimed |
| CN-1046280-C | Novel thiophenesulfonylurea derivative and herbicidal composition containing the same | KOREA RES INST CHEM TECH (KR) | 1999-11-10 | — | — | CN | claimed |
| US-5792788-A | FOR TREATMENT OF CARDIAC DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-11 | — | — | US | claimed |
| US-5726127-A | Thiophenesulfonylurea derivatives and herbicidal composition containing the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-03-10 | — | — | US | claimed |
| US-5698539-A | PLANT SAFENING AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | claimed |
| CN-1134421-A | Substituted thiophenesulfonylureas and-thioureas, processes for their preparation, their use as medicament or diagnostic, and medicament containing them | HOECHST AG (DE) | 1996-10-30 | — | — | CN | claimed |
| CN-1134701-A | Novel thiophenesulfonylurea derivatives and herbicidal compositions containing the same | KOREA RES INST CHEM TECH (KR) | 1996-10-30 | — | — | CN | claimed |
| US-5488027-A | Herbicide-safener combinations containing sulfonylurea or imidazolinone herbicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-30 | — | — | US | claimed |
| US-5430006-A | Herbicidal substituted thienylsulphonylureas | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-04 | — | — | US | claimed |
| WO-1995013276-A1 | NOVEL THIOPHENESULFONYLUREA DERIVATIVES AND HERBICIDAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-05-18 | — | — | WO | claimed |
| EP-0575435-A1 | THIOPHENESULFONYLUREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1993-12-29 | — | — | EP | claimed |
| WO-1992016525-A1 | THIOPHENESULFONYLUREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-10-01 | — | — | WO | claimed |
| JP-6199848-A | — | — | None | — | — | JP | disclosed |
| EP-0001514-A2 | Herbicidal sulfonamides, and preparation and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035755-A1 | METHOD OF CONTROLLING WEEDS IN A TURF GRASS BY USING SULFONYLUREA COMPOUNDS | NOTUM, CYP4F3, CYP4F2 | CYP2D6 48/4885CYP2C9 53/4885CYP2C19 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.