Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 18/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 18/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PDE1A | P54750 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306556 | 0.87 | PDE3B (0.45) | ALDH1A1PDE3BPDE3AKDM4EMEN1 | |
| SCHEMBL7317431 | 0.85 | PDE3B (0.40) | ALDH1A1SMN1; SMN2PDE3BPDE3AKDM4E | |
| SCHEMBL7318435 | 0.80 | PDE3B (0.42) | ALDH1A1PDE3BPDE3AKDM4EMEN1 | |
| SCHEMBL7317266 | 0.79 | PDE3B (0.48) | ALDH1A1SMN1; SMN2PDE3BPDE3AKDM4E | |
| SCHEMBL10376741 | 0.77 | PDE3B (0.54) | ALDH1A1PDE3BPDE3AKDM4EMEN1 | |
| SCHEMBL10376988 | 0.77 | PDE3B (0.54) | ALDH1A1PDE3BPDE3AKDM4EMEN1 | |
| SCHEMBL7318827 | 0.77 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2PDE3BPDE3AKDM4E | |
| SCHEMBL10376673 | 0.76 | PDE3B (0.54) | ALDH1A1PDE3BPDE3AKDM4EMEN1 | |
| SCHEMBL7308504 | 0.76 | PDE3B (0.41) | ALDH1A1PDE3BPDE3AKDM4EMEN1 | |
| SCHEMBL7309387 | 0.76 | PDE6D (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |