Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 17/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 17/20 | 0.40 |
| ▸ | PDE2A | O00408 | 5/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306556 | 0.85 | PDE3B (0.45) | PDE3BPDE3APDE2AP2RY12ALDH1A1 | |
| SCHEMBL7315555 | 0.85 | ALDH1A1 (0.42) | PDE3BPDE3APDE2AP2RY12ALDH1A1 | |
| SCHEMBL7316157 | 0.81 | PDE3B (0.40) | PDE3BPDE3APDE2AP2RY12ALDH1A1 | |
| SCHEMBL7311484 | 0.80 | PDE3B (0.47) | PDE3BPDE3AP2RY12ALDH1A1KDM4E | |
| SCHEMBL7319480 | 0.78 | PDE3B (0.44) | PDE3BPDE3APDE2AP2RY12ALDH1A1 | |
| SCHEMBL10377348 | 0.77 | PDE3B (0.52) | PDE3BPDE3APDE2AP2RY12ALDH1A1 | |
| SCHEMBL7319377 | 0.76 | PDE6D (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7312666 | 0.75 | PDE4A (0.46) | PDE3BPDE3APDE2AP2RY12ALDH1A1 | |
| SCHEMBL7318435 | 0.75 | PDE3B (0.42) | PDE3BPDE3APDE2AP2RY12ALDH1A1 | |
| SCHEMBL7308504 | 0.75 | PDE3B (0.41) | PDE3BPDE3APDE2AP2RY12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |