Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.53 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1902756 | 1.00 | FAAH (0.53) | FAAHSPHK2SPHK1OPRD1 | |
| Hydrochloric Acid SCHEMBL11904574 | 0.98 | FAAH (0.52) | FAAHSPHK2SPHK1OPRD1 | |
| Hydrochloric Acid SCHEMBL2278177 | 0.98 | FAAH (0.52) | FAAHSPHK2SPHK1OPRD1 | |
| SCHEMBL5967967 | 0.95 | OPRD1 (0.53) | FAAHSPHK2SPHK1OPRD1 | |
| Hydrochloric Acid SCHEMBL8686948 | 0.93 | OPRD1 (0.52) | FAAHSPHK2SPHK1OPRD1 | |
| SCHEMBL11990400 | 0.89 | GBA1 (0.49) | — | |
| SCHEMBL11199979 | 0.86 | SPHK2 (0.50) | FAAHSPHK2SPHK1 | |
| SCHEMBL2997593 | 0.86 | — | — | |
| SCHEMBL5530480 | 0.86 | — | — | |
| SCHEMBL15648682 | 0.84 | SPHK2 (0.51) | FAAHSPHK2SPHK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4902684-A | Benzazepine and benzothiazepine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1990-02-20 | — | — | US | disclosed |
| WO-1989012633-A1 | BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | E.R. SQUIBB & SONS, INC. (US) | 1989-12-28 | — | — | WO | disclosed |