Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315669 | 1.00 | PDK2 (0.39) | PDK2SLC1A2SLC1A1SLC1A3HTT | |
| SCHEMBL7325928 | 0.89 | SLC1A3 (0.41) | PDK2SLC1A2SLC1A1SLC1A3HTT | |
| SCHEMBL7325924 | 0.89 | SLC1A3 (0.41) | PDK2SLC1A2SLC1A1SLC1A3HTT | |
| SCHEMBL7316689 | 0.88 | KIF11 (0.36) | PDK2SLC1A2SLC1A1SLC1A3HTT | |
| SCHEMBL7316697 | 0.88 | KIF11 (0.36) | PDK2SLC1A2SLC1A1SLC1A3HTT | |
| SCHEMBL7313467 | 0.87 | PDK2 (0.36) | PDK2SLC1A2SLC1A1SLC1A3POLB | |
| SCHEMBL7313476 | 0.87 | PDK2 (0.36) | PDK2SLC1A2SLC1A1SLC1A3POLB | |
| SCHEMBL7319571 | 0.86 | PDK2 (0.43) | PDK2SLC1A2SLC1A1SLC1A3LMNA | |
| SCHEMBL7319567 | 0.86 | PDK2 (0.43) | PDK2SLC1A2SLC1A1SLC1A3LMNA | |
| SCHEMBL7312498 | 0.86 | PDK2 (0.39) | PDK2SLC1A2SLC1A1SLC1A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |