⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7390146 | 0.92 | — | — | |
| SCHEMBL10859050 | 0.89 | — | — | |
| SCHEMBL7396313 | 0.89 | — | — | |
| SCHEMBL7393552 | 0.88 | — | — | |
| SCHEMBL7393554 | 0.88 | — | — | |
| SCHEMBL10632027 | 0.87 | — | — | |
| SCHEMBL10625515 | 0.86 | — | — | |
| SCHEMBL7312366 | 0.86 | GABRG2 (0.64) | — | |
| SCHEMBL7307204 | 0.86 | MEN1 (0.55) | — | |
| SCHEMBL7395838 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109921-B1 | BENZODIAZEPINE RECEPTORS AND THEIR PREPARATION | A/S FERROSAN (DK) | 1988-03-02 | — | — | EP | claimed |
| US-4507313-A | Oxadiazolyl-imidazo-[1,4]benzodiazepines and their use in treatment of diseases of the central nervous system | A/S FERROSAN (DK) | 1985-03-26 | — | — | US | claimed |
| EP-0109921-B1 | BENZODIAZEPINE RECEPTORS AND THEIR PREPARATION | A/S FERROSAN (DK) | 1988-03-02 | — | — | EP | disclosed |
| US-4507313-A | Oxadiazolyl-imidazo-[1,4]benzodiazepines and their use in treatment of diseases of the central nervous system | A/S FERROSAN (DK) | 1985-03-26 | — | — | US | disclosed |
| EP-0109921-A1 | Benzodiazepine receptors and their preparation | A/S FERROSAN (DK) | 1984-05-30 | — | — | EP | disclosed |