Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GABRP | O00591 | 1/20 | 0.55 |
| ▸ | GABRD | O14764 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.55 |
| ▸ | GABRE | P78334 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393030 | 0.93 | MEN1 (0.52) | MEN1GABRPGABRDALDH1A1CYP1A2 | |
| SCHEMBL10630005 | 0.90 | GABRA1 (0.52) | MEN1GABRPGABRDALDH1A1CYP1A2 | |
| SCHEMBL10632027 | 0.90 | — | — | |
| SCHEMBL7312366 | 0.89 | GABRG2 (0.64) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7398879 | 0.89 | GABRP (0.49) | MEN1GABRPGABRDALDH1A1CYP1A2 | |
| SCHEMBL10632268 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL7391492 | 0.88 | GABRP (0.49) | MEN1GABRPGABRDALDH1A1CYP1A2 | |
| SCHEMBL7394437 | 0.88 | GABRP (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10630010 | 0.87 | GABRP (0.55) | MEN1GABRPGABRDALDH1A1CYP1A2 | |
| SCHEMBL10627732 | 0.87 | GABRA1 (0.52) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109921-B1 | BENZODIAZEPINE RECEPTORS AND THEIR PREPARATION | A/S FERROSAN (DK) | 1988-03-02 | — | — | EP | claimed |
| US-4507313-A | Oxadiazolyl-imidazo-[1,4]benzodiazepines and their use in treatment of diseases of the central nervous system | A/S FERROSAN (DK) | 1985-03-26 | — | — | US | claimed |
| US-4507313-A | Oxadiazolyl-imidazo-[1,4]benzodiazepines and their use in treatment of diseases of the central nervous system | A/S FERROSAN (DK) | 1985-03-26 | — | — | US | disclosed |