Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 19/20 | 0.66 |
| ▸ | PDE3A | Q14432 | 19/20 | 0.66 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7314774 | 0.97 | PDE3B (0.66) | PDE3BPDE3AP2RY12NPC1LMNA | |
| SCHEMBL7317096 | 0.92 | PDE3B (0.61) | PDE3BPDE3AP2RY12NPC1LMNA | |
| SCHEMBL7303290 | 0.86 | PDE3B (0.71) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7312151 | 0.84 | PDE3B (0.68) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7308217 | 0.84 | PDE3B (0.68) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7312169 | 0.83 | PDE3B (0.47) | PDE3BPDE3ANPC1LMNAALOX15 | |
| SCHEMBL7307748 | 0.83 | PDE3B (0.48) | PDE3BPDE3ANPC1LMNAALOX15 | |
| SCHEMBL7313147 | 0.82 | PDE3B (0.86) | PDE3BPDE3AP2RY12PDE4APDE4B | |
| SCHEMBL7319436 | 0.82 | PDE3B (0.56) | PDE3BPDE3A | |
| SCHEMBL7306899 | 0.80 | PDE3B (0.98) | PDE3BPDE3AP2RY12PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |