Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 7/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAF1 | P04049 | 2/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312169 | 0.88 | PDE3B (0.47) | PDE3BPDE3ALMNANPC1ALOX15 | |
| SCHEMBL7315783 | 0.83 | PDE3B (0.66) | PDE3BPDE3ALMNANPC1ALOX15 | |
| SCHEMBL7312258 | 0.82 | PDE3B (0.42) | PDE3BPDE3ALMNANPC1ALOX15 | |
| Acetic Acid SCHEMBL7314774 | 0.82 | PDE3B (0.66) | PDE3BPDE3ALMNANPC1ALOX15 | |
| SCHEMBL7319436 | 0.80 | PDE3B (0.56) | PDE3BPDE3AKDM4E | |
| SCHEMBL7319732 | 0.78 | PDE3B (0.42) | PDE3BPDE3ALMNANPC1ALOX15 | |
| SCHEMBL7316751 | 0.78 | PDE3B (0.45) | PDE3BPDE3ANPC1MAPK1HSD17B10 | |
| SCHEMBL7317096 | 0.78 | PDE3B (0.61) | PDE3BPDE3ALMNANPC1ALOX15 | |
| SCHEMBL7317020 | 0.78 | PDE3B (0.51) | PDE3BPDE3ALMNANPC1ALOX15 | |
| SCHEMBL7310542 | 0.76 | PDE3B (0.50) | PDE3BPDE3ALMNANPC1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |