Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 2/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307748 | 0.88 | PDE3B (0.48) | PDE3BPDE3AKDM4EMAPK1ATM | |
| SCHEMBL7312258 | 0.85 | PDE3B (0.42) | PDE3BPDE3AKDM4EMAPK1LMNA | |
| SCHEMBL7315783 | 0.83 | PDE3B (0.66) | PDE3BPDE3AMAPK1LMNANPC1 | |
| SCHEMBL7319732 | 0.82 | PDE3B (0.42) | PDE3BPDE3AKDM4EMAPK1LMNA | |
| SCHEMBL7320379 | 0.82 | PDE3B (0.60) | PDE3BPDE3A | |
| Acetic Acid SCHEMBL7314774 | 0.81 | PDE3B (0.66) | PDE3BPDE3AMAPK1LMNANPC1 | |
| SCHEMBL7319436 | 0.77 | PDE3B (0.56) | PDE3BPDE3AKDM4EHPGD | |
| SCHEMBL7311914 | 0.77 | PDE3B (0.51) | PDE3BPDE3AKDM4ELMNANPC1 | |
| SCHEMBL7312688 | 0.77 | PDE3B (0.51) | PDE3BPDE3AKDM4E | |
| SCHEMBL7315793 | 0.77 | PDE3B (0.58) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |