SCHEMBL731592

SCHEMBL731592

CC(=O)C(=O)OC(C)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.32
GAA P10253 1/20 0.32
CYP2C9 P11712 1/20 0.32
PKM P14618 1/20 0.32
CYP2C19 P33261 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KMT2A Q03164 1/20 0.32
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP9 P14780 1/20 0.31
MMP13 P45452 1/20 0.31
SLC7A5 Q01650 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30
THPO P40225 1/20 0.30
FFAR3 O14843 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL8512781 0.97 TSHR (0.36) TSHRTP53CYP1A2GAACYP2C9
SCHEMBL9129538 0.81 TSHR (0.39) TSHRTHPO
SCHEMBL9435536 0.81 TP53 (0.38) TSHRTP53CYP1A2GAACYP2C9
SCHEMBL526912 0.80 TSHR (0.45) TSHRTP53CYP1A2GAACYP2C9
SCHEMBL9842552 0.80 TSHR (0.45) TSHRTP53CYP1A2GAACYP2C9
Ammonia Solution, Strong SCHEMBL18138980 0.78 TSHR (0.43) TSHRTP53TDP1SLC7A5
Methyl Alcohol SCHEMBL28174876 0.78 TSHR (0.43) TSHRTP53TDP1SLC7A5
SCHEMBL140866 0.78
SCHEMBL140867 0.78
SCHEMBL1764859 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106111173-A A kind of for being prepared the catalyst of pyruvate by lactate and preparing the method for pyruvate 厦门市净屋环保科技有限公司 2016-11-16 CN claimed
US-20240238255-A1 KL1333 FOR USE IN MEDICINE YUNGJIN PHARM. CO., LTD (KR) 2024-07-18 US disclosed
US-12012437-B2 Methods of treating mitochondrial disorders THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-18 US disclosed
CN-114732007-B Sperm cell process, apparatus and related media compositions 英格朗公司 2024-04-12 CN disclosed
EP-4350323-A2 SYSTEM FOR PREPARING AN OUTPUT SAMPLE COMPRISING A DEFINED CONCENTRATION OF AN INFECTIOUS AGENT FOR DOWNSTREAM TESTING Avails Medical, Inc. (US) 2024-04-10 EP disclosed
EP-3968021-B1 SYSTEM FOR PREPARING AN OUTPUT SAMPLE COMPRISING A DEFINED CONCENTRATION OF AN INFECTIOUS AGENT FOR DOWNSTREAM TESTING AVAILS MED INC (US) 2024-04-03 EP disclosed
EP-4340831-A1 KL1333 FOR USE IN MEDICINE Abliva AB (SE) 2024-03-27 EP disclosed
CN-117597429-A Method and system for assessing the quality of flow dynamics in sperm-containing samples 康奈尔大学 2024-02-23 CN disclosed
US-20240042440-A1 METHODS FOR EVALUATING RHEOTAXIS QUALITY IN A SPERM-CONTAINING SAMPLE AND SYSTEMS THEREFOR CORNELL UNIVERSITY 2024-02-08 US disclosed
US-11857588-B2 Reproductive cell maintenance system MEMBRANE PROTECTIVE TECHNOLOGIES, INC. (US) 2024-01-02 US disclosed
US-4450841-A Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders THOMAS JEFFERSON UNIVERSITY (US) 1984-05-29 US disclosed
US-4451251-A Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders THOMAS JEFFERSON UNIVERSITY (US) 1984-05-29 US disclosed
US-4445886-A FLUOROCARBON EMULSION THOMAS JEFFERSON UNIVERSITY (US) 1984-05-01 US disclosed
US-4446154-A Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders THOMAS JEFFERSON UNIVERSITY (US) 1984-05-01 US disclosed
US-4446155-A Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders THOMAS JEFFERSON UNIVERSITY (US) 1984-05-01 US disclosed
US-4445500-A Stroke treatment utilizing extravascular circulation of oxygenated synthetic nutrients to treat tissue hypoxic and ischemic disorders THOMAS JEFFERSON UNIVERSITY (US) 1984-05-01 US disclosed
US-4445888-A FLUOROCARBON EMULSION THOMAS JEFFERSON UNIVERSITY (US) 1984-05-01 US disclosed
US-4445887-A FLOROCARBON EMULSION THOMAS JEFFERSON UNIVERSITY (US) 1984-05-01 US disclosed
US-4353867-A COMPUTERIZED QUANTITATIVE ANALYZER LUZZANA MASSIMO 1982-10-12 US disclosed
EP-0052718-A1 Method and apparatus for the determination of substances in biological solutions by differential pH measurement Luzzana, Massimo (IT) 1982-06-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238255-A1 KL1333 FOR USE IN MEDICINE CKMT1A; CKMT1B, SLC25A1, MT-ND3 TSHR 2627/4885TP53 2722/4885CYP1A2 3882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.