Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | GPR34 | Q9UPC5 | 8/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315990 | 1.00 | PPARG (0.56) | PPARGGPR34MMP9MMP8MME | |
| SCHEMBL3789073 | 0.84 | PPARG (0.68) | PPARGGPR34MMP9MMP8MME | |
| SCHEMBL3789070 | 0.84 | PPARG (0.68) | PPARGGPR34MMP9MMP8MME | |
| SCHEMBL20268332 | 0.82 | MMP9 (0.78) | PPARGGPR34MMP9MMP8MME | |
| SCHEMBL3787413 | 0.82 | PPARG (0.56) | PPARGGPR34MMP9MMP8MME | |
| SCHEMBL20268330 | 0.82 | MMP9 (0.78) | PPARGGPR34MMP9MMP8MME | |
| SCHEMBL3787409 | 0.82 | PPARG (0.56) | PPARGGPR34MMP9MMP8MME | |
| SCHEMBL11513382 | 0.80 | MMP9 (0.58) | PPARGGPR34MMP9MMP8MME | |
| SCHEMBL16541091 | 0.79 | SIGMAR1 (0.60) | PPARGMMP9MMP8MMEACE | |
| SCHEMBL6330507 | 0.79 | TACR1 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100366605-C | Compounds to treat alzheimer's disease | ELAN PHARM INC (US) | 2008-02-06 | — | — | CN | disclosed |
| CN-1447789-A | Compounds for treating alzheimer's disease | ELAN PHARM INC (US) | 2003-10-08 | — | — | CN | disclosed |
| US-5492910-A | AIDS TREATMENT | BRISTOL-MYERS SQUIBB CO. (US) | 1996-02-20 | — | — | US | disclosed |