SCHEMBL731598

SCHEMBL731598

c1ccc(-c2ccco2)nc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.73
ALDH1A1 P00352 8/20 0.73
HSD17B10 Q99714 6/20 0.67
PKM P14618 5/20 0.67
MAPT P10636 5/20 0.67
RAB9A P51151 4/20 0.67
GFER P55789 1/20 0.67
KDM4C Q9H3R0 1/20 0.67
POLB P06746 6/20 0.62
SMN1; SMN2 Q16637 4/20 0.62
TP53 P04637 4/20 0.62
NPC1 O15118 3/20 0.62
LMNA P02545 4/20 0.54
BLM P54132 3/20 0.54
CCR1 P32246 2/20 0.54
CCR5 P51681 2/20 0.54
CCR8 P51685 2/20 0.54
CYP1A2 P05177 1/20 0.54
METAP1 P53582 1/20 0.54
HIF1A Q16665 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29836037 1.00 KDM4E (0.73) KDM4EALDH1A1HSD17B10PKMMAPT
SCHEMBL337077 0.89
Hexane SCHEMBL8812661 0.88 KDM4E (0.59) KDM4EALDH1A1HSD17B10PKMMAPT
Oxazole SCHEMBL27635121 0.86 KDM4E (0.58) KDM4EALDH1A1HSD17B10PKMMAPT
SCHEMBL17746299 0.82
SCHEMBL17821196 0.80 ALDH1A1 (0.55) KDM4EALDH1A1HSD17B10PKMMAPT
SCHEMBL3477187 0.80 KDM4E (0.59) KDM4EALDH1A1HSD17B10PKMMAPT
SCHEMBL21061751 0.80 KDM4E (0.68) KDM4EALDH1A1HSD17B10PKMMAPT
Dipyridyl SCHEMBL391569 0.75 KDM4E (0.93) KDM4EALDH1A1HSD17B10PKMMAPT
Dipyridyl SCHEMBL31695013 0.75 KDM4E (0.93) KDM4EALDH1A1HSD17B10PKMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025099728-A1 CONJUGATES COMPRISING OLIGOMERIC DUFFING OSCILLATORS AND USES THEREOF MOLECULAR MACHINES CORPORATION LTD. (IL) 2025-05-15 WO claimed
CN-117203324-A Novel yeast strains and their use in controlling plant pathogens 爱农创投有限公司 2023-12-08 CN claimed
CN-112264089-B SAPO-11 Ni-loaded composite catalyst and preparation method and application thereof 江南大学 2021-11-23 CN claimed
CN-112264089-A SAPO-11 Ni-loaded composite catalyst and preparation method and application thereof 江南大学 2021-01-26 CN claimed
US-9957280-B2 Luminescent compound and electroluminescent device exhibiting thermally activated delayed fluorescence SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US claimed
US-20160168162-A1 LUMINESCENT COMPOUND AND ELECTROLUMINESCENT DEVICE EXHIBITING THERMALLY ACTIVATED DELAYED FLUORESCENCE SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-16 US claimed
WO-2005010081-A1 AROMATIC MONOMER-AND CONJUGATED POLYMER-METAL COMPLEXES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-02-03 WO claimed
US-20050014023-A1 Aromatic monomer- and conjugated polymer-metal complexes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-01-20 US claimed
US-6392047-B1 COUPLING OF THE CORRESPONDING AROMATIC COMPOUND WITH AN AROMATIC BORON COMPOUND CLARIANT GMBH (DE) 2002-05-21 US claimed
EP-1200373-A1 METHOD FOR PRODUCING BIARYLS USING PALLADAPHOSPHACYCLOBUTANE CATALYSIS Clariant GmbH (DE) 2002-05-02 EP claimed
WO-2001004076-A1 METHOD FOR PRODUCING BIARYLS USING PALLADAPHOSPHACYCLOBUTANE CATALYSIS CLARIANT GMBH (DE) 2001-01-18 WO claimed
US-5489685-A CATALYTIC REACTION OF TRIMETHYLSILYLACETYLENE WITH HALOGENATED HYDROXY PYRIDINE ESTER, THEN INCUBATION WITH ACID AND TREATMENT WITH STRONG BASE OR HALIDE FOR CYCLIZATION MERCK & CO., LTD. (US) 1996-02-06 US claimed
CN-122036731-A CB1 receptor inverse agonist compound, pharmaceutical composition, preparation method and application thereof 北京康辰药业股份有限公司 2026-05-15 CN disclosed
CN-112239468-B Metal-free solvent-free synthesis of fused pyridine heterocycles and biomedical applications thereof 印多尔印度理工学院 2025-05-27 CN disclosed
WO-2025099728-A1 CONJUGATES COMPRISING OLIGOMERIC DUFFING OSCILLATORS AND USES THEREOF MOLECULAR MACHINES CORPORATION LTD. (IL) 2025-05-15 WO disclosed
CN-117143108-B 8-bromo-2-methylbenzofuran [2,3-b ] pyridine and synthetic method 蒲城欧得新材料有限公司 2024-03-19 CN disclosed
EP-0388429-A1 FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS ABBOTT LABORATORIES (US) 1990-09-26 EP disclosed
EP-0320628-A1 Substituted furan compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase ABBOTT LABORATORIES (US) 1989-06-21 EP disclosed
WO-1989004299-A1 FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS ABBOTT LABORATORIES (US) 1989-05-18 WO disclosed
US-3937712-A MICROBIOCIDES BOEHRINGER INGELHEIM GMBH (DT) 1976-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160168162-A1 LUMINESCENT COMPOUND AND ELECTROLUMINESCENT DEVICE EXHIBITING THERMALLY ACTIVATED DELAYED FLUORESCENCE OCIAD2, OCIAD1, JUND KDM4E 2598/4885ALDH1A1 660/4885HSD17B10 2141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.