⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29836037 | 0.89 | KDM4E (0.73) | — | |
| SCHEMBL731598 | 0.89 | KDM4E (0.73) | — | |
| SCHEMBL17746299 | 0.83 | — | — | |
| Hexane SCHEMBL8812661 | 0.78 | KDM4E (0.59) | — | |
| Oxazole SCHEMBL27635121 | 0.76 | KDM4E (0.58) | — | |
| SCHEMBL1445253 | 0.76 | MAPK1 (0.53) | — | |
| SCHEMBL30463614 | 0.76 | MAPK1 (0.53) | — | |
| SCHEMBL5301835 | 0.76 | SIRT1 (0.52) | — | |
| SCHEMBL3060017 | 0.75 | KDM4E (0.58) | — | |
| SCHEMBL31064975 | 0.75 | ALDH1A1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12523648-B1 | Fluorescent indicators for calcium metal ion detection | ION Biosciences (US) | 2026-01-13 | — | — | US | claimed |
| US-9810700-B1 | Fluorogenic calcium ion indicators and methods of using the same | AAT BIOQUEST, INC. (US) | 2017-11-07 | — | — | US | claimed |
| US-8097632-B2 | Blocking hedgehog protein transduction signal passageway using alkaloid steroid | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2012-01-17 | — | — | US | claimed |
| WO-2010138421-A1 | HEXAHYDROCYCLOPENTYL[f]INDAZOLE REVERSED AMIDES AND DERIVATIVES AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2010-12-02 | — | — | WO | claimed |
| US-20080058298-A1 | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE | 2008-03-06 | — | — | US | claimed |
| US-20060142245-A1 | Inhibitors of hedgehog signaling pathways, compositions and uses related thereto | JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2006-06-29 | — | — | US | claimed |
| US-20060020020-A1 | Regulators of the hedgehog pathway, compositions and uses related thereto | CURIS, INC. (US) | 2006-01-26 | — | — | US | claimed |
| US-20040127474-A1 | Regulators of the hedgehog pathway, compositions and uses related thereto | CURIS, INC. (US) | 2004-07-01 | — | — | US | claimed |
| US-6432970-B2 | REDUCE CELL SENSITIVITY | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE | 2002-08-13 | — | — | US | claimed |
| JP-2002511415-A | — | — | 2002-04-16 | — | — | JP | claimed |
| US-20020006931-A1 | INHIBITORS OF HEDGEHOG SIGNALING PATHWAYS, COMPOSITIONS AND USES RELATED THERETO | THE JOHNS HOPKINS UNIVERSITY | 2002-01-17 | — | — | US | claimed |
| US-20010034337-A1 | Regulators of the hedgehog pathway, compositions and uses related thereto | CURIS, INC. | 2001-10-25 | — | — | US | claimed |
| EP-1067939-A1 | USE OF STEROIDAL ALKALOID DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING PATHWAYS | The Johns Hopkins University, School of Medicine, Office of Technology Licencing (US) | 2001-01-17 | — | — | EP | claimed |
| WO-1999052534-A1 | USE OF STEROIDAL ALKALOID DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING PATHWAYS | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 1999-10-21 | — | — | WO | claimed |
| US-4346159-A | Photosensitive element for electrophotography | FUJI XEROX CO., LTD. (JP) | 1982-08-24 | — | — | US | claimed |
| JP-55015426-A | — | — | None | — | — | JP | disclosed |
| WO-2026097169-A1 | METHOD FOR SULFONATING PRECURSOR MONOMERS IN THE SYNTHESIS OF ADVANCED ANIONIC SULFONATED POLYPHENYLENE POLYMERS | IONOMR INNOVATIONS INC. (CA) | 2026-05-15 | — | — | WO | disclosed |
| US-4535169-A | 5H-6-oxo-2,3,4,4a,7,7a-hexahydropyrano[2,3-b]pyrrole and the preparation thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1985-08-13 | — | — | US | disclosed |
| US-4346159-A | Photosensitive element for electrophotography | FUJI XEROX CO., LTD. (JP) | 1982-08-24 | — | — | US | disclosed |
| JP-S5515426-A | PYRANOPYRROLE DERIVATIVE | YOSHITOMI PHARMACEUT IND LTD | 1980-02-02 | — | — | JP | disclosed |