Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.35 |
| ▸ | EBP | Q15125 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | SCN1A | P35498 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317309 | 0.92 | CACNA1B (0.37) | CACNA1BABCB1CYP3A4EBPSIGMAR1 | |
| SCHEMBL7314456 | 0.89 | ABCB1 (0.42) | CACNA1BABCB1CYP3A4EBPSIGMAR1 | |
| SCHEMBL7315667 | 0.88 | CACNA1B (0.38) | CACNA1BABCB1CYP3A4EBPSIGMAR1 | |
| SCHEMBL7306036 | 0.88 | EBP (0.41) | CACNA1BEBPSIGMAR1 | |
| SCHEMBL7301603 | 0.88 | CACNA1B (0.36) | CACNA1BABCB1CYP3A4EBPSIGMAR1 | |
| SCHEMBL7313731 | 0.87 | CACNA1B (0.38) | CACNA1BABCB1CYP3A4EBPSIGMAR1 | |
| SCHEMBL7309087 | 0.86 | CACNA1B (0.34) | CACNA1BABCB1EBPSIGMAR1 | |
| SCHEMBL7311990 | 0.86 | EBP (0.33) | CACNA1BEBPSIGMAR1DRD2DRD3 | |
| SCHEMBL7309476 | 0.86 | EBP (0.36) | CACNA1BEBPSIGMAR1 | |
| SCHEMBL7302555 | 0.85 | EBP (0.33) | CACNA1BEBPSIGMAR1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |