Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 19/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18167755 | 0.95 | PDK2 (0.56) | PDK2THRB | |
| SCHEMBL21732768 | 0.91 | PDK2 (0.61) | PDK2 | |
| SCHEMBL27623798 | 0.90 | PDK2 (0.51) | PDK2THRBTDP1 | |
| SCHEMBL24074658 | 0.88 | PDK2 (0.50) | PDK2 | |
| SCHEMBL22876054 | 0.87 | PDK2 (0.50) | PDK2THRBTDP1 | |
| SCHEMBL14970795 | 0.86 | PDK2 (0.50) | PDK2THRBTDP1 | |
| SCHEMBL7322862 | 0.86 | PDK2 (0.50) | PDK2THRBTDP1 | |
| SCHEMBL17816650 | 0.84 | PDK2 (0.49) | PDK2THRBTDP1 | |
| SCHEMBL30838761 | 0.84 | PDK2 (0.44) | PDK2THRBTDP1 | |
| SCHEMBL28623493 | 0.84 | PDK2 (0.44) | PDK2THRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101492442-A | Complex diaryl fluorene material, preparation and application method thereof | UNIV NANJING POSTS & TELECOMM (CN) | 2009-07-29 | — | — | CN | disclosed |
| CN-1769269-A | End-blocked triarylamine and carbazoles material, handling method and uses | UNIV FUDAN (CN) | 2006-05-10 | — | — | CN | disclosed |
| CN-1743409-A | End capped thiofuran small-molecule and polymer material, treating method and use thereof | UNIV FUDAN (CN) | 2006-03-08 | — | — | CN | disclosed |
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |