Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 17/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17816650 | 0.98 | PDK2 (0.49) | PDK2THRBTDP1SLC6A2SLC6A4 | |
| SCHEMBL28607030 | 0.88 | PDK2 (0.49) | PDK2THRBTDP1SLC6A2SLC6A4 | |
| SCHEMBL23996970 | 0.86 | PDK2 (0.45) | PDK2THRBTDP1 | |
| SCHEMBL7316307 | 0.86 | PDK2 (0.59) | PDK2THRBTDP1 | |
| SCHEMBL27623798 | 0.86 | PDK2 (0.51) | PDK2THRBTDP1 | |
| SCHEMBL14970795 | 0.85 | PDK2 (0.50) | PDK2THRBTDP1 | |
| SCHEMBL17816776 | 0.85 | PDK2 (0.46) | PDK2THRBTDP1 | |
| SCHEMBL5474585 | 0.84 | PDK2 (0.47) | PDK2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22876054 | 0.82 | PDK2 (0.50) | PDK2THRBTDP1 | |
| SCHEMBL30345614 | 0.82 | THRB (0.52) | PDK2THRBTDP1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162824-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ALLELIX NEUROSCIENCE INC. | 2000-12-19 | — | — | US | disclosed |
| WO-1999041227-A1 | TRICYCLIC COMPOUNDS AS GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-08-19 | — | — | WO | disclosed |