SCHEMBL14970795

SCHEMBL14970795

OC1(c2ccc(-c3cccc(-c4ccc(C5(O)c6ccccc6-c6ccccc65)cc4)c3)cc2)c2ccccc2-c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 18/20 0.50
MEN1 O00255 1/20 0.42
ESR1 P03372 1/20 0.42
KMT2A Q03164 1/20 0.42
THRB P10828 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24074654 0.91 PDK2 (0.43) PDK2
SCHEMBL22876054 0.90 PDK2 (0.50) PDK2MEN1KMT2ATHRBTDP1
SCHEMBL14970800 0.90 PDK2 (0.45) PDK2MEN1ESR1KMT2ATHRB
SCHEMBL12938477 0.90 PDK2 (0.45) PDK2MEN1ESR1KMT2ATHRB
SCHEMBL31576206 0.90 PDK2 (0.45) PDK2MEN1ESR1KMT2ATHRB
SCHEMBL4822450 0.89 MEN1 (0.45) PDK2MEN1ESR1KMT2A
SCHEMBL27623798 0.86 PDK2 (0.51) PDK2MEN1KMT2ATHRBTDP1
SCHEMBL7316307 0.86 PDK2 (0.59) PDK2THRBTDP1
SCHEMBL7322862 0.85 PDK2 (0.50) PDK2THRBTDP1
SCHEMBL24074658 0.84 PDK2 (0.50) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210388216-A1 Crosslinked Aromatic Polymer Compositions and Methods of Making Insulation Coatings For Use on Components Subject to High Temperature, Corrosive and/or High Voltage End Applications GREENE, TWEED TECHNOLOGIES, INC. 2021-12-16 US disclosed
EP-2909253-B1 CROSS-LINKED ORGANIC POLYMER COMPOSITIONS Delsper LP (US) 2021-11-10 EP disclosed
US-20200172669-A1 Crosslinkable Aromatic Polymer Compositions for Use in Additive Manufacturing Processes and Methods for Forming the Same GREENE, TWEED TECHNOLOGIES, INC. 2020-06-04 US disclosed
US-20170183445-A1 Anti-Extrusion Compositions for Sealing and Wear Components Delsper LP 2017-06-29 US disclosed
US-20170183445-A1 Anti-Extrusion Compositions for Sealing and Wear Components Delsper LP 2017-06-29 US disclosed
US-9475938-B2 Anti-extrusion compositions for sealing and wear components DELSPER, LP (US) 2016-10-25 US disclosed
US-9475938-B2 Anti-extrusion compositions for sealing and wear components DELSPER, LP (US) 2016-10-25 US disclosed
EP-2780392-B1 CROSSLINKING COMPOUNDS FOR HIGH GLASS TRANSITION TEMPERATURE POLYMERS GREENE TWEED & CO INC (US) 2016-06-29 EP disclosed
US-20150344688-A1 Anti-Extrusion Compositions for Sealing and Wear Components Delsper LP 2015-12-03 US disclosed
US-20150344688-A1 Anti-Extrusion Compositions for Sealing and Wear Components Delsper LP 2015-12-03 US disclosed
US-20140323668-A1 CROSSLINKING COMPOUNDS FOR HIGH GLASS TRANSITION TEMPERATURE POLYMERS GREENE, TWEED & CO. (US) 2014-10-30 US disclosed
US-20140323668-A1 CROSSLINKING COMPOUNDS FOR HIGH GLASS TRANSITION TEMPERATURE POLYMERS GREENE, TWEED & CO. (US) 2014-10-30 US disclosed
US-20140316079-A1 Cross-Linked Organic Polymers For Use as Elastomers in High Temperature Applications Delsper LP 2014-10-23 US disclosed
US-20140316079-A1 Cross-Linked Organic Polymers For Use as Elastomers in High Temperature Applications Delsper LP 2014-10-23 US disclosed
US-20140284850-A1 Cross-Linked Organic Polymer Compositions and Methods for Controlling Cross-Linking Reaction Rate and of Modifying Same to Enhance Processability Delsper LP 2014-09-25 US disclosed
US-20140284850-A1 Cross-Linked Organic Polymer Compositions and Methods for Controlling Cross-Linking Reaction Rate and of Modifying Same to Enhance Processability Delsper LP 2014-09-25 US disclosed
WO-2014145834-A1 CROSS-LINKED ORGANIC POLYMERS FOR USE AS ELASTOMERS Delsper LP (US) 2014-09-18 WO disclosed
US-20140213742-A1 Anti-Extrusion Compositions for Sealing and Wear Components Delsper LP (US) 2014-07-31 US disclosed
US-20140213742-A1 Anti-Extrusion Compositions for Sealing and Wear Components Delsper LP (US) 2014-07-31 US disclosed
WO-2013074120-A1 CROSSLINKING COMPOUNDS FOR HIGH GLASS TRANSITION TEMPERATURE POLYMERS GREENE, TWEED & CO. (US) 2013-05-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140284850-A1 Cross-Linked Organic Polymer Compositions and Methods for Controlling Cross-Linking Reaction Rate and of Modifying Same to Enhance Processability AOX1, DUOX2, HAO2 PDK2 890/4885MEN1 4482/4885ESR1 535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.